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・ First-class citizen
・ First-class cricket
・ First-class function
・ First-class message
・ First-come, first-served
・ First-countable space
・ First-degree atrioventricular block
・ First-difference estimator
・ First-dose phenomenon
・ First-e Group
・ First-foot
・ First-generation jet fighter
・ First-generation programming language
・ First-hitting-time model
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First-in-man study
・ First-level NUTS of the European Union
・ First-move advantage
・ First-move advantage in chess
・ First-mover advantage
・ First-order
・ First-order election
・ First-order fluid
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・ First-order logic
・ First-order partial differential equation
・ First-order predicate
・ First-order reaction
・ First-order reduction
・ First-order reliability method


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First-in-man study : ウィキペディア英語版
First-in-man study
A first-in-man study is a clinical trial where a medical procedure, previously developed and assessed through ''in vitro'' or animal testing, or through mathematical modelling is tested on human subjects for the first time. Sometimes, this is called a Phase 0 study.
Such studies present particular risks to the human subjects as was signally the case in the TGN1412 trial in 2006. Consequently, there are ethical issues as to whether such trials should be performed on healthy volunteers, who have nothing to gain beyond a fee, or on patients who have a chance of enjoying a health benefit.
==Bibliography==

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抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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